BioCell Collagen Benefits
Discover how BioCell Collagen® supports your body from the inside out. Clinically researched and backed by nature, it promotes healthier skin, joints, hair, nails, and more — helping you look, feel, and move your best every day.
The scalp is identical to the skin except that it also contains hair follicles that produce hair. Collagen and hyaluronic acid (HA) are essential for nourishment and hydration of the dermal layers of the scalp for healthy, lustrous hair. BioCell Collagen® contains a unique matrix of bioavailable collagen and HA.*
Gums are integral to tooth health as well. Our gums (gingiva) are made of similar building blocks of skin, including collagen, chondroitin and hyaluronic acid. BioCell Collagen® contains a unique matrix of bioavailable collagen, chondroitin and HA.*
Perhaps you remember the term “vitreous humor” from science class. It’s the term for the transparent gelatinous tissue filling the eyeball behind the lens made up of primarily collagen type II and hyaluronic acid (HA). BioCell Collagen® contains a unique matrix of bioavailable collagen and HA.*
Collagen and HA are vital components of skin that decline as we age and are responsible for the skin’s moisture, suppleness, elasticity, vibrancy, and beauty. BioCell Collagen® contains a unique matrix of bioavailable collagen and HA. BioCell Collagen® was shown in clinical studies to significantly reduce facial fine lines & wrinkles, crow’s feet, skin dryness, while improving skin elasticity.*
BioCell Collagen® is comprised of a unique matrix of primarily collagen type II peptides, chondroitin sulfate and HA, mirroring components of human body.
Fingernails and toenails are made of the same building block as hair – keratin. BioCell Collagen® is rich in sulfur-containing amino acids that promote keratin production for growth of strong, beautiful nails. As important as the actual nail is, the nail bed is also crucial for nail health. The nail bed is comprised of connective tissue made up of collagen and HA. BioCell Collagen® contains a unique matrix of bioavailable collagen and HA.*
BioCell Collagen® Benefits
More Active Joints and Younger-Looking Skin
Feed Your Skin & Joints!
What is BioCell Collagen®?
BioCell Collagen® is a clinically studied dietary ingredient composed of naturally-occurring hydrolyzed collagen type II peptides, chondroitin sulfate, hyaluronic acid. BioCell’s unique matrix is not a blend of individual ingredients. Clinical studies confirm that BioCell Collagen® promotes active joints, youthful-looking skin, and healthy connective tissues. Various research studies, including seven human clinical trials, support the safety, efficacy, and bioavailability of BioCell Collagen®. BioCell Collagen® is patented and unlike other collagen and hyaluronic acid ingredients on the market. Look for the BioCell Collagen® trademark logo of authenticity proudly displayed on the labels of finished products that contain BioCell Collagen®.*
It is important to note that not all collagen and hyaluronic acid ingredients are created equal. There are several collagen and hyaluronic acid supplements available in the market that lack clinical evidence and that have a very different molecular makeup than BioCell Collagen®. BioCell’s unique composition is patented and has undergone human clinical trials proving its efficacy. BioCell Collagen® utilizes a patented Bio-Optimization™ process, which ensures remarkable bioavailability as well as rapid absorption into the body. The synergy of biomolecules found in BioCell Collagen ®’s unique matrix offers multi-dimensional nutritional support for the health of connective tissues of the skin, joint, tendon, and ligament.*
BioCell Collagen® Joint Health & Mobility Studies
BioCell Collagen® has a comprehensive approach to joint health, one that not only targets cartilage, but the related tendons, ligaments, and synovial fluid. Glucosamine and chondroitin formulations were the standard of care in joint health for more than two decades with limited success. The big question on the mind of dieticians and health care practitioners today is what’s next in joint health. BioCell Collagen® offers significant advantages with its advanced, unique composition, which mirrors human articular cartilage for the comprehensive maintenance of healthy joint function. BioCell Collagen®’s uniquely differentiated properties provide broader, more complete, and superior nutritional support. Results from human clinical trials on 185 men and women who took 2000 mg daily showed BioCell Collagen® safely improved joint comfort, mobility, and quality of life.*
Joint Health Benefits: BioCell Collagen® is clinically shown to:
- Promote joint comfort & mobility*
- Enhance post-exercise recovery*
- Support skin & joint collagens (type I, II & III)*
- Help stimulate cartilage renewal*
- Promote tendon and ligament connective tissue recovery following intense exercise*
Clinically Proven Results:
BioCell Collagen® offers a patented, comprehensive solution for healthy joints through multiple mechanisms of action.
Clinically Proven in Randomized Double Blind Placebo Controlled Human Clinical Trials
Sports Nutrition Study: BioCell Collagen® Post-Workout Recovery
In an 80 subject, randomized, double-blind, placebo-controlled trial for joint health, investigators tested the tolerability and efficacy of BioCell Collagen® supplementation. The participants were divided into two groups and administered either 2 g of BioCell Collagen or placebo for 70 days. Compared to placebo, the BioCell group had a significant reduction of joint discomfort on days 35 (p = 0.017) and 70 (p < 0.001). Furthermore, the BioCell group experienced a significant improvement in physical activities compared to the placebo group on days 35 (p = 0.007) and 70 (p < 0.001). BioCell Collagen was well tolerated and found to be effective, thereby improving mobility and quality of life. The peer-reviewed study was published in the Journal of Agriculture and Food Chemistry. (https://pubs.acs.org/doi/10.1021/jf205295u) (Schauss et al., 2012). These results were similar to the results of another earlier double-blind placebo-controlled trial tested on sixteen people. (Kalman et al., 2004).
BioCell Collagen® was tested in a pilot randomized, double-blind placebo-controlled study in recreationally active people. Participants took three grams of BioCell Collagen® over six weeks before an upper-body bench press challenge. Participants experienced favorable improvements in stress resilience and recovery after bouts of intense resistance exercise without any reported side effects (Lopez et al., 2014).*
A cartilage mirror: replenishing structural components essential for healthy joints
BioCell Collagen® provides the building blocks of macromolecular collagen, HA, and chondroitin sulfate essential for the health of cartilage, synovial fluid, and tendon and ligament connective tissue.
BioCell Collagen® Skin Beauty-from-Within Studies
BioCell Collagen® Ingestion
Clinically shown to:
- Significantly reduces facial lines and wrinkles*
- Reduce crow’s feet*
- Improve skin elasticity*
- Reduce skin dryness*
- Increase skin collagen & hyaluronic acid*
Clinically Tested
1. In a 12-week study, women who took 1000 mg (1 g) of BioCell Collagen daily had 76% less dryness/scaling, and their fine lines and wrinkles had reduced by 13.2% when compared to baseline levels. Additionally, both collagen levels and microcirculation were significantly improved. The outcome of this study was published in the Clinical Interventions in Aging journal (https://doi.org/10.2147/CIA.S32836)*
2. In one of the most substantial studies of a skin health supplement, 1000 mg of BioCell Collagen® was found to visibly reduce common signs of skin aging, including lines and wrinkles, within 12 weeks of daily use. The findings reported in this randomized, double-blind, placebo-controlled clinical trial included a measurable improvement in signs of aging in women, represented by increased skin elasticity, reduction of crow’s feet, and improvement in depth and number of fine lines and wrinkles. The full findings of the peer-reviewed study are published in the journal of Alternative Therapies in Health and Medicine. (2019). (https://www.ncbi.nlm.nih.gov/pubmed/31221944)
BioCell Collagen® is Uniquely Bioavailable and Bioactive
Research suggests that the ingestion of BioCell Collagen® stimulates chondrocytes (cartilage producing cells) and fibroblasts (skin producing cells) in the renewal of cartilage and skin. Moreover, BioCell Collagen® was shown to have a concentration-dependent inhibition of hyaluronidase. This enzyme degrades hyaluronic acid, which can contribute to signs of aging on the skin and loss of viscoelasticity of joint synovial fluid. BioCell Collagen® also attenuates deleterious changes in biomarkers including creatine kinase, lactate dehydrogenase, and C-reactive protein adding further clues into its mechanism of action.*
BioCell Collagen® Hyaluronic Acid Absorption Study
Hyaluronic Acid (HA) is in virtually all tissues of the body. In the joint, HA plays two essential roles. First, it acts as a key structural molecule to form healthy, functional cartilage. Second, HA is a major component of synovial fluid, the lubricant found in our joints that allows smooth and easy movement. In a 28-day bioavailability study in humans showed that ingestion of BioCell Collagen® (1500 mg/day) led to a 60 times increase in HA levels at steady state.*
BioCell Collagen® Ingestion Before and After Photos
Human Skin Study (2011) on facial aging signs (1000mg/day, 12 weeks). Results not typical, individual results may vary.
What is the difference between BioCell Collagen® and other collagen ingredients?
BioCell Collagen® is not just an ordinary collagen ingredient. BioCell Collagen® is a branded ingredient composed of naturally-occurring hydrolyzed collagen type II peptides, chondroitin sulfate, hyaluronic acid. BioCell’s unique matrix is not a blend of individual ingredients. The synergy of biomolecules found in BioCell’s unique matrix plays a major role in its efficacy. Various studies, including seven human clinical trials, prove the safety, efficacy, bioavailability of BioCell Collagen®. Look for BioCell’s trademarked logos of authenticity proudly displayed on the labels of finished consumer products that contain the BioCell Collagen® ingredient.*
Is all collagen the same, the only differentiator being whether it’s Type I, II, III, IV, etc.?
No, not all collagen is the same or equivalent. The collagen type, source, molecular size, composition, and manufacturing process differentiate the various dietary supplement collagen products in their indications and efficacy. BioCell Technology, the supplier of BioCell Collagen, has invested in almost two decades of clinical trials and research and development activities. BioCell Technology pioneered the applications of hydrolyzed collagen type II, chondroitin sulfate, and hyaluronic acid matrix compositions and was awarded several patents for its invention.*
1. Effect of BioCell Collagen®, on Improving Joint Comfort: A Randomized, Double-Blind, Placebo-Controlled Trial.
- Eighty subjects were divided into two groups and administered either 2 g of BioCell Collagen® supplement or placebo for ten weeks.
- Compared to placebo, the BioCell group had a significant improvement of joint comfort on days 35 (p = 0.017) and 70 (p < 0.001).
- BioCell group experienced a significant improvement in physical activities compared to the placebo group on days 35 (p = 0.007) and 70 (p < 0.001).
- BioCell Collagen was well tolerated and found to be effective, thereby improving mobility and quality of life.
The peer-reviewed study was published in the Journal of Agriculture and Food Chemistry. (https://pubs.acs.org/doi/10.1021/jf205295u) (Schauss et al., 2012).
Results of study – Min. 30% improvement in 71% of subjects taking BioCell Collagen
2. A Randomized Double-Blind Clinical Pilot Trial Evaluating the Safety and Efficacy of BioCell Collagen® in Adults for Joint Comfort
- Sixteen subjects split evenly into two groups, ingested 1000 mg of BioCell Collagen® twice daily (2 g) or placebo for eight weeks.
- As compared to the placebo group, the BioCell group showed 40% improvement
- No adverse events associated with BioCell Collagen.
The study details were presented at the international conference of Experimental Biology, 2004, Washington, DC.
Results of the study – 40% improvement
3. BioCell Supplement on Subjective Discomfort (1999)
- This 89 subject, prospective, crossover double-blind clinical study compared 2 g daily supplementation of the BioCell ingredient versus placebo over three months.
- Out of the 89 participants who complained of subjective discomfort of various types, 80 of them (89%) reported some level of improvement within 45 days of taking the BioCell supplement.
- In contrast, only one subject on placebo had improved.
- No adverse events with the BioCell supplement. (1999 unpublished study)
Results of study – Effective in 89% of subjects
4. Effects of BioCell Collagen® on connective tissue protection and functional recovery from exercise in healthy adults.
- In this pilot study, 3 g of BioCell Collagen supplement daily for six weeks enhanced recovery following weight training exercise and favorably impacted certain bio-markers of tendon and ligament connective tissue.
The study findings were published in the Journal of the International Society of Sports Nutrition (JISSN): http://www.jissn.com/content/11/S1/P48
1. Ingestion of BioCell Collagen®; enhanced blood microcirculation and reduced facial aging signs.
- Twenty-six healthy female subjects aged 35 to 59 years of various ethnic origin.
- Subjects ingested 1 g of BioCell Collagen® daily in two equally divided doses, morning and evening for 12 weeks.
- BioCell Collagen® demonstrated the following results:
- Significant reduction of facial lines and wrinkles
- Significant reduction of facial skin dryness and scaling
- Significant increase in facial dermal collagen content and microcirculation
- The study findings are published in the journal of Clinical Interventions in Aging (2012).
(http://www.ncbi.nlm.nih.gov/pubmed/22956862)
2. BioCell Collagen® Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial..
- One hundred thirteen healthy female subjects aged 39 to 59 years.
- Subjects ingested 1 g of BioCell Collagen® daily in two equally divided doses, morning and evening for 12 weeks.
- BioCell Collagen® demonstrated the following results compared to a placebo:
- Significantly reduced facial lines and wrinkles (P = .019) and crow’s feet lines and wrinkles (P = .05)
- Significantly increased skin elasticity (P = .008) and cutaneous collagen content (P < .001) by 12%
- Significantly improved indicators associated with a more youthful skin appearance based on visual grading and wrinkle width (P = .046)
- Decreased skin dryness and erythema
- The study findings are published in the journal of Alternative Therapies in Health and Medicine (2019).
(https://www.ncbi.nlm.nih.gov/pubmed/31221944)
